I've done it for addons how you would expect... dropping a file into the game may have uncontrollable results. My first opinion is that it isn't worth the effort and the doing so is likely a violation of the TOS.
If you decide to do so, I would suspect its as simple as dropping a font layout over the original. Again, back it up cause its likely to cause problems and might be detected on patching.
A hint: Thanks to Doom, Rift uses the WAD file distribution system IIRC.
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